Pro-/Seminar: Persistent and Emerging Topics of Virtual Screening

Lecturer:

Priv.-Doz. Dr. Michael Hutter

 

Maximum number of participants:

10

Lecture:

proseminar/seminar taking place during the lecture period on Mondays, 10:15 am - 11:45 am, building E2 1, room 007, start date tba

 

Preliminary meeting and placement of the topics:

Monday, October 22nd, 2018, 10:15 am, E2 1, room 007

Requirements:

Successful participation in one of the following courses:
Bioinformatik II, Softwarewerkzeuge der Bioinformatik,
Modern Methods in Drug Discovery, Bioinformatics III,
Structural Bioinformatics

Conditions for certification:

Successful presentation, regular participation (at least 60% of talks)

Leistungspunkte/Credits:

5 (proseminar) or 7 (seminar)

Topics:

  1. Protein-ligand docking and scoring
  2. Concepts of chemical similarity
  3. In silico ADMET and bioavailability
  4. Rational drug design and adverse effects
  5. Anti-targets
  6. Tackling biosynthetic pathways of pathogens
  7. Model organisms
  8. Prediction of drug-likeness
  9. Prediction of drugable binding pockets
  10. Blockbuster drugs vs. emerging targets