Bioinformatics 3

Registration

For organizational reasons (add to MS Teams group), if you want to participate, please register by email to Kerstin Gronow-Pudelek.

Requirements

Familiarity with contents of Bioinformatik I and II. The students will have to complete programming assignments e.g. with Python. This course can be taken as part of the Master Program Bioinformatics.

Content

The course will cover methodological aspects of integrated biology and systems biology:

• protein-protein interaction networks (mathematical graphs, Bayesian networks)
• analysis of protein complexes (density fitting, Fourier transformation)
• transcriptional regulatory networks (Boolean networks) including epigenetic modifications and micro RNAs
• dynamic simulation of cellular processes (differential equation solvers, stochastic simulations)
• metabolic networks (linear algebra)

Textbook

V. Helms, Principles of Computational Cell Biology, Wiley (2019)

Certification

Students need to pass the written final exam that will be scheduled near the end of the winter semester or the re-exam that will be scheduled at the beginning of the following summer semester.

Condition for participation in the final exam

At least half of the total points of the assignments has to be reached, which for 10 assignments means that students have to accumulate at least 500 points in total.

Lectures

Lectures take place on Tuesdays from 12:15 pm to 2:00 pm and on Thursdays from 2:15 to 4:00 pm in building E2.1 room 001. The lecture slides are available in the Microsoft Teams group in the “General” channel under “Files”.

Assignments

Assignments will be uploaded to the Microsoft Teams group in the “General” channel under “Files” according to the schedule below. Our Assignment Guide contains more information about our assignment policies that should be read before beginning with an assignment.

Tutorials

Tutorials take place online in Microsoft Teams after the submission of their corresponding assignment. The time slot is Tuesdays from 4:00 pm to 5:00 pm.