Special-topic Lecture Biosciences: Cellular Programs WS 2020/21


Dr. Pratiti Bhadra, Andreas Denger, Nicolas Künzel, Trang Do Huang Thu


UPDATE: Until further notice, all lectures will take place only online!!!

Two separate groups up to 14 students each: Tuesday, 10:15 am – 11:45 am or 4:15 pm – 5:45 pm, building E2 1, room 001, starting on November 3rd, 2020; lecture slides and student presentations will be available online.


Monday, 4:30 pm – 6:00 pm


Oral re-exams will take place at CBI, room 1.06, on April 16th, 2021, for those students who failed or missed the first exam. Details will be sent by email.
Students not physically present in Saarland can take an online exam instead. Please regard the registration deadline of April 9th, 2021, for this exam at LSF. A later registration will not be accepted.


There will be two alternative dates for the written exam, February 18th and March 4th, and an online exam taking place on March 5th for those who are still in their home countries:

February 18th, 10:00 am, building E2 1, seminar rooms 001 and 007  or

March 4th, 10:00 am, building E2 1, seminar rooms 001 and 007  or

Online oral exam: March 5th, details were sent by email.

Exam results of February 18th

Exam results of March 4th

For organizational reasons, I ask for feedback on the selected exam date by January 24th to Kerstin Gronow-Pudelek

Exam registration: only by email to Kerstin Gronow-Pudelek, no registration in LSF, for the exam on February 18th until February 11th, for the exam on March 4th and the oral exam on March 5th until February 25th.

A re-exam will probably take place in the first lecture week in April 2021.


This course can be used as a “Spezialvorlesung der Biowissenschaften/Special-topic Lecture Biosciences”. You need to register for this course as soon as possible sending an email to Kerstin Gronow-Pudelek whereby you indicate which time you prefer, Tuesday 10.15 am or Tuesday, 4:15 pm.

UPDATE: Until further notice, all lectures will take place only online!

In addition, due to the Corona pandemic restrictions, a registration at LSF until October 30th, 2020, is mandatory for all students who want to attend the lecture in presence on the campus. This is independent of the exam registration.


no formal requirements, but solid prior knowledge about

  • cellular networks
  • genetics
  • cell biology
  • omics technologies


a. biological content
– circadian rhythms
– cell cycle
– cell differentiation/cell reprogramming
– development of cancer
b. bioinformatics content
– gene expression analysis
– DNA methylation analysis
– time series analysis
– gene ontology and pathway annotation
– interaction networks
– application of clustering techniques
– construction of gene-regulatory networks

Conditions for certification:

  1. There will be n=5 biweekly assignments. Students need to answer questions and write short essays about topics covered in the lecture and in assigned research papers. There are three possible grades: excellent, pass, failed. Students need to get a “pass” grade on at least n-1 assignments or n-3 “pass” and one “excellent” grade.
  2. A written final exam of 120 min. will be offered at the end of the semester. Online participants who either do not live in Saarland during the semester or who have a medical certificate for not being able to attend the lectures in person can take an oral exam instead.
  3. Students need to present at least once during the lecture or via video-conferencing on the content of an assigned research paper (20 min. presentation and 10 min. discussion).


An averaged score will be computed from the mark of the final exam (counts 2/3) and the graded presentation (counts 1/3). This yields the grade of certification (“Schein”).


5 (2 V + 1 Ü)


This course is taught in English language.

Topics for student presentations

Here you will find the topics for your presentations.


Lecture 1, Nov. 3 pdf
Lecture 2, Nov. 10 pdf Assignment 1
Lecture 3, Nov. 17 pdf
Lecture 4, Nov. 24 pdf Assignment 2
Lecture 5, Dec. 1 pdf Assignment 3
Lecture 6, Dec. 8 pdf
Lecture 7, Dec. 15 pdf Assignment 4
Lecture 8, Jan. 5 pdf
Lecture 9, Jan. 12 pdf Assignment 5
Lecture 10, Jan. 19 pdf
Lecture 11, Jan. 26 pdf Assignment 6
Lecture 12, Feb. 2