Special-topic Lecture Biosciences: Cellular Programs WS 2020/21

Tutors:

Dr. Pratiti Bhadra, Andreas Denger, Nicolas Künzel, Trang Do Huang Thu

Lecture:

Two separate groups up to 14 students each: Tuesday, 10:15 am – 11:45 am or 4:15 pm - 5:45 pm, building E2 1, room 001, starting on November 3rd, 2020; lecture slides and student presentations will be available online.

Tutorial:

tba

Exam:

Dates of the exam: tba

 

Information:

This course can be used as a “Spezialvorlesung der Biowissenschaften/Special-topic Lecture Biosciences”. You need to register for this course until October 26th sending an email to Kerstin Gronow-Pudelek whereby you indicate which time you prefer, Tuesday 10.15 am or Tuesday, 4:15 pm

Requirements:

no formal requirements, but solid prior knowledge about

  • cellular networks
  • genetics
  • cell biology
  • omics technologies

Content:

a. biological content
- circadian rhythms
- cell cycle
- cell differentiation/cell reprogramming
- development of cancer
b. bioinformatics content
- gene expression analysis
- DNA methylation analysis
- time series analysis
- gene ontology and pathway annotation
- interaction networks
- application of clustering techniques
- construction of gene-regulatory networks

Conditions for certification:

  1. There will be n=5 biweekly assignments. Students need to answer questions and write short essays about topics covered in the lecture and in assigned research papers. There are three possible grades: excellent, pass, failed. Students need to get a “pass” grade on at least n-1 assignments or n-3 “pass” and one “excellent” grade.
  2. A written final exam of 120 min. will be offered at the end of the semester. Online participants who either do not live in Saarland during the semester or who have a medical certificate for not being able to attend the lectures in person can take an oral exam instead.
  3. Students need to present at least once during the lecture or via video-conferencing on the content of an assigned research paper (20 min. presentation and 10 min. discussion).

Schein/Certification:

An averaged score will be computed from the mark of the final exam (counts 2/3) and the graded presentation (counts 1/3). This yields the grade of certification (“Schein”).

Leistungspunkte/Credits:

5 (2 V + 1 Ü)

Language

This course is taught in English language.

Lectures:

Lecture 1, Nov. 3 pdf
Lecture 2, Nov. 10 pdf Assignment 1
Lecture 3, Nov. 17 pdf
Lecture 4, Nov. 24 pdf
Lecture 5, Dec. 1 pdf  
Lecture 6, Dec. 8 pdf
Lecture 7, Dec. 15 pdf
Lecture 8, Jan. 5 pdf
Lecture 9, Jan. 12 pdf
Lecture 10, Jan. 19 pdf
Lecture 11, Jan. 26 pdf
Lecture 12, Feb. 2 pdf

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