Special-topic Lecture Biosciences: Cellular Programs SS 2019


Dr. Pratiti Bhadra, Daria Gaidar, Markus Hollander, Nicolas Künzel, Dr. Duy Nguyen


Tuesday, 10:15 am – 11:45 am, building E2 1, room 007, starting on April 16th


Wednesday, 2:00 pm - 4:00 pm, starting on May 8th, 2019, building E2 1, room 007

Next tutorial: Wednesday, June 26th


Dates of the tests: May 14th, June 11th and July 9th, 10:15 am in building E1 3, lecture hall 001

Test 1: Scale of grades

The results of test 1 have been sent by email.

Test 2: Results and scale of grades

Exam registration on LSF until June 4th, 2019, is mandatory.


This course can be used as a “Spezialvorlesung der Biowissenschaften/Special-topic Lecture Biosciences”


no formal requirements, but solid prior knowledge about

  • cellular networks
  • genetics
  • cell biology
  • omics technologies


a. biological content
    - circadian rhythms
    - cell cycle
    - cell differentiation/cell reprogramming
    - development of cancer
b. bioinformatics content
    - microarray expression analysis
    - DNA methylation analysis
    - time series analysis
    - gene ontology and pathway annotation
    - interaction networks
    - application of clustering techniques
    - construction of gene-regulatory networks

Conditions for certification:

  1.  UPDATE! This regulation replaces the previous one! There will be n=5 biweekly assignments. Students need to answer questions and write short essays about topics covered in the lecture and in assigned research papers. There are three possible grades: excellent, pass, failed. Students need to get a “pass” grade on at least n-1 assignments or n-3 “pass” and one “excellent” grade.
  2. There will be three 45-minutes tests on different parts of the lecture. Students need to pass at least two out of the three tests. Tests will cover the content of the lecture and of the assigned research papers.
  3. Students need to present at least once during the lecture on the content of an assigned research paper (20 min. presentation and 10 min. discussion).


An averaged score will be computed from the best two results of the three tests and the graded presentation. This yields the grade of certification (“Schein”). There will be no final exam.


5 (2 V + 1 Ü)


This course is taught in English language.



Lecture 1, April 16 pdf ppt    
Lecture 2, April 23 pdf ppt  Assignment 1  
Lecture 3, April 30 pdf ppt    
Lecture 4, May 7 pdf ppt    
Lecture 5, May 14 pdf ppt

Assignment 2

Test 1, place: E1 3, lecture hall 001 
Lecture 6, May 21 pdf ppt    Tutorial 2: May 22nd
Lecture 7, May 28 pdf  ppt Assignment 3 Tutorial on May 29th to discuss the solutions of test #1
Lecture 8, June 4 pdf  ppt    Tutorial 3: June 5th
Lecture 9, June 11 pdf  ppt   Test 2, place: E1 3, lecture hall 001
Lecture 10, June 18 pdf ppt  Assignment 4  Tutorial on June 19th to discuss the solutions of test #2
Lecture 11, June 25 pdf ppt   Tutorial 4: June 26th
Lecture 12, July 2        
Lecture 13, July 9        Test 3, place: E1 3, lecture hall 001
Lecture 14: July 16