Special-topic Lecture Bioinformatics: Processing of Biological Data

Tutors:

Rahmad Akbar, Daria Gaidar, Maryam Nazarieh, Duy Nguyen, Kerstin Neininger, Thorsten Will

Lecture:

Tuesday, 10:15 am - 11:45 am, building E2 1, room 007

Please regard the alternative dates and places of lectures in the schedule below!

First lecture: Friday, April 21st, 1:00 pm

Tutorial:

Tuesday, 12:45 am - 02:00 pm, building E2 1, room 007.

Information:

This course can be used as a "Spezialvorlesung der Bioinformatik/Special-topic Lecture Bioinformatics"

Results of the exam of July 18th, 2017.

Results of the re-exam of October 20th, 2017.

Requirements:

Intermediate programming skills in Python

Content:

    • clustering of data
    • principal component analysis
    • differential expression analysis
    • removal and correction of data outliers; prediction of missing values; BEclear method
    • processing of proteomics data; imputation of missing values
    • peak assignment
    • protein structure data (Protein DataBank); thermal mobility; titration states; hydration sites; PDBcheck
    • molecular dynamics simulations; time correlation of snapshots
    • analysis of multi-dimensional data

Conditions for certification:

Students need to pass the final exam.

There will be about six bi-weekly graded assignments and tutorial sessions. Students need to get at least 50% of the points from the assignments to be admitted to the final exam. 

Schein/Certification:

Students need to pass the written final exam that will be scheduled near the end of the summer semester or the re-exam that will be scheduled at the beginning of the following winter semester.

Leistungspunkte/Credits:

5 (2 V + 1 Ü)

Language

This course is taught in English language.

Lectures:

Lecture 1, April 21 (Friday, 1:00 pm - 3:00 pm) ppt pdf    
Lecture 2, April 26 (Wednesday, 8:30 am - 10:00 am) ppt pdf    
Lecture 3, May 2 ppt pdf Assign1 Supplement
Lecture 4, May 9 ppt pdf    
Lecture 5, May 19 (Friday, 2:15 pm - 4:00 pm, E2 1, room 106) ppt pdf  Assign2  Supplement
Lecture 6, May 23 ppt pdf    
Lecture 7, May 30 ppt pdf Assign3 Supplement
Lecture 8, June 6 ppt pdf    
Lecture 9, June 13 ppt pdf  Assign4  Supplement
Lecture 10, June 20 ppt pdf    
Lecture 11, June 27 ppt pdf Assign5  Supplement
Lecture 12, July 4 ppt pdf    
July 11 no lecture      
July 18, 11 am - 1 pm Exam