Bioinformatics 3

Registration

For organizational reasons (add to MS Teams group), if you want to participate, please register by email to Kerstin Gronow-Pudelek.

Requirements

Familiarity with contents of Bioinformatik I and II. This course can be taken as part of the Master Program Bioinformatics.

Content

The course will cover methodological aspects of integrated biology and systems biology:

• protein-protein interaction networks (mathematical graphs, Bayesian networks)
• analysis of protein complexes (density fitting, Fourier transformation)
• transcriptional regulatory networks (Boolean networks) including epigenetic modifications and micro RNAs
• dynamic simulation of cellular processes (differential equation solvers, stochastic simulations)
• metabolic networks (linear algebra)

Textbook

V. Helms, Principles of Computational Cell Biology, Wiley (2019)

Certification

Students need to pass the written final exam taking place on July 23 or the re-exam that will be scheduled at the beginning of the following winter semester.

Condition for participation in the final exam

At least half of the points from the two mini tests that take place during the semester must be achieved in order to be admitted to the exam. Test 1 will take place after lecture 8 (Friday, May 8, 12:30, place tba) and test 2 after lecture 16 (Friday, June 12, 12:30, place tba). In addition, six assignments are given out, which are not mandatory and will not be corrected; the solutions will be discussed in the tutorials.

Lectures

Lectures take place on Tuesdays from 10:15 pm to 12:00 and on Thursdays from 2:15 to 4:00 pm in building E2.1 room 001. The lecture slides are available in the Microsoft Teams group in the “General” channel under “Files”.

Assignments

Assignments will be uploaded to the Microsoft Teams group in the “General” channel under “Files”.

Tutorials

Tutorials take place one week after the corresponding assignment was given out. Time and place to be announced.