Bioinformatics 3

Lecturer:

Prof. Dr. Volkhard Helms

Tutors

Daria Gaidar, Maryam Nazarieh, Duy Nguyen, Thorsten Will

Lecture:

Monday, 2:15 pm – 4:00 pm and Friday, 1:15 pm – 3:00 pm, building E2 1, room 007

Tutorial:

Monday, 12:00 pm – 2:00 pm, E2 1, room 007

Exam:

Monday, March 7th, 10:00 am – 01:00 pm, building E1 3, lecture hall 001 – see slide 2 of lecture V24

Re-exam

The re-exam will take place on Friday, April 22nd, 10:00 am in building E2.1, room 007.

Requirements:

Familiarity with contents of Bioinformatik I and II. The students will have to complete programming assignments with Python. This course can be taken as part of the Master program Bioinformatics.

Content:

The course will cover methodological aspects of integrated biology and systems biology:

  • protein-protein interaction networks (mathematical graphs, Bayesian networks)
  • analysis of protein complexes (density fitting, Fourier transformation)
  • transcriptional regulatory networks (Boolean networks) including epigenetic processes and micro RNAs
  • dynamic simulation of cellular processes (differential equation solvers, stochastic simulations)
  • metabolic networks (linear algebra)

Schein/Certification:

Students need to pass the written final exam that will be scheduled near the end of the winter semester or the re-exam that will be scheduled at the beginning of the following summer semester.

Condition for participation in the final exam:

At least half of the points of the assignments. Solutions have to be returned at the beginning of the following Friday´s lecture. In addition each student has to solve one of these problems on the blackboard.

Textbook:

V. Helms, Principles of Computational Cell Biology, Wiley (2008)

Leistungspunkte/Credits:

9 (4 V + 2 Ü)

Language

This course is taught in English language.

Lectures:

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