Lecturer: Prof. Dr. Volkhard Helms
Lecture: Monday, 2:15 pm – 4:00 pm and Friday, 1:15 pm – 3:00 pm, building E2 1, room 007
Tutorial: Monday, 12:00 pm – 14:00 pm, E2 1, room 007
Requirements: familiarity with contents of Bioinformatik I and II. The students will have to complete programming assignments with Python. This course can be taken as part of the Master program Bioinformatics.
Contents: the course will cover methodological aspects of integrated biology and systems biology:
- protein-protein interaction networks (mathematical graphs, Bayesian networks)
- analysis of protein complexes (density fitting, Fourier transformation)
- transcriptional regulatory networks (Boolean networks) buy term papers including epigenetic processes and micro RNAs
- dynamic simulation of cellular processes (differential equation solvers, stochastic simulations)
- metabolic networks (linear algebra)
Condition for certification: There will be four 45-minutes tests on different parts of the lecture. An averaged score will be computed from the best three results of the four tests. This score will count 50% for the grade of certification (“Schein”). The other 50% are taken from the mark in the final exam (120 min) that will (mostly) cover the material of the assignments.
Condition for the participation in the final exam: (a) successful participation in 3 out of the 4 tests, (b) at least half of the points of the assignments. Solutions have to be returned at the beginning of the following Friday´s lecture. In addition each student has to solve one of these problems on the blackboard.
Textbook: V. Helms, Principles of Computational Cell Biology, Wiley (2008)
Date of the examination: Friday, February 1, 2013, 1:00 pm – 3:00 pm, E2 1, room 007
Leistungspunkte/Credits:
9 (4 V + 2 Ü)
This course is taught in English language.
Lectures:
| Lecture 1, October 15 |
ppt | Assignment | Supplement | |
| Lecture 2, October 19 |
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| Lecture 3, October 22 |
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| Lecture 4, October 26 |
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| Lecture 5, October 29 |
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| Lecture 6, November 2 |
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| Lecture 7, November 5 |
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| Lecture 8, November 9 |
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| Lecture 9, November 12 |
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| Lecture 10, November 16 |
ppt | Lecture from 2:15 pm – 3:15 pm | ||
| Lecture 11, November 19 |
ppt | NO TUTORIAL TODAY | ||
| Lecture 12, November 23 |
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| Lecture 13, November 26 |
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| Lecture 14, November 30 |
ppt | no tutorial on December 3 | ||
| Lecture 15, December 10 |
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| Lecture 16, December 14 |
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| Lecture 17, December 17 |
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| Lecture 18a, January 7 |
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| Lecture 18b, January 11 |
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| Lecture 19, January 14 |
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| Lecture 20, January 18 |
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| Lecture 21, January 21 |
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| Lecture 22, January 25 |
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| January 28 | no lecture | |||
| Lecture 23, February 1 |
Final exam |