Special-topic Lecture Bioinformatics: Processing of Biological Data WS 21/22

Monday, January 31st, 2022, 10:00 am – 12:00; building E1 3, HS 002LSF exam registration is mandatory by January 24th, 2022.

International students not physically present in Saarland can take an online exam instead. In this case, please, send an email until Thursday, January 20^th, 10:00 am, to Kerstin Gronow-Pudelek.

This course can be used as a “Spezialvorlesung der Bioinformatik/Special-topic Lecture Bioinformatics”

Intermediate programming skills in Python

1. • clustering of data
   • principal component analysis
   • differential expression analysis
   • removal and correction of data outliers; prediction of missing values
   • processing of proteomics data; imputation of missing values
   • peak assignment
   • shape detection
   • functional annotation
   • protein structure data (Protein DataBank); thermal mobility; titration states; hydration sites; PDBcheck
   • molecular dynamics simulations; time correlation of snapshots
   • multi-variate analysis
   • analysis of multi-dimensional data; data integration

Students need to pass the final exam.

There will be about six bi-weekly graded assignments and tutorial sessions. Students need to get at least 50% of the points from the assignments to be admitted to the final exam.

Students need to pass the final exam that will be scheduled near the end of the winter semester or the re-exam that will be scheduled at the beginning of the following summer semester; written final exam -> oral exam

5 (2 V + 1 Ü)

This course is taught in English language.