Lecturer:
Tutors:
Lecture:
First lecture: May 5th, 2020;
Students intending to take this course should send an
e-mail to kerstin.gronow-p@bioinformatik.uni-saarland.de
so that they can be registered as participants in
Microsoft Teams in the course named “PBD-SS2020”.
Tutorial:
Video Lectures
The username is <your student ID>@uni-saarland.de (e.g. s9example@uni-saarland.de) and the password is the same one you use for the LSF/HISPOS or other university logins.
More information on how to use Microsoft Teams at Saarland University can be found here.
Exam:
Students not physically present in Saarland can take an online exam instead. Please regard the registration deadline of July 24th, 2020, for this exam at LSF. A later registration will not be possible.
Information:
This course can be used as a “Spezialvorlesung der Bioinformatik/Special-topic Lecture Bioinformatics”
Requirements:
Intermediate programming skills in Python
Content:
- clustering of data
- principal component analysis
- differential expression analysis
- removal and correction of data outliers; prediction of missing values
- processing of proteomics data; imputation of missing values
- peak assignment
- shape detection
- functional annotation
- protein structure data (Protein DataBank); thermal mobility; titration states; hydration sites; PDBcheck
- molecular dynamics simulations; time correlation of snapshots
- multi-variate analysis
- analysis of multi-dimensional data; data integration
Conditions for certification:
Students need to pass the final exam.
There will be about six bi-weekly graded assignments and tutorial sessions. Students need to get at least 50% of the points from the assignments to be admitted to the final exam.
Schein/Certification:
Leistungspunkte/Credits:
5 (2 V + 1 Ü)
Language
This course is taught in English language.
Lectures:
Lecture 1, May 5 | ppt1-audio ppt2-audio ppt3-audio ppt4-audio |
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Lecture 2, May 12 | ppt1-audio ppt2-audio ppt3-audio |
Assignment 1 Supplement 1 |
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Lecture 3, May 19 | ppt1-audio ppt2-audio ppt3-audio |
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Lecture 4, May 26 | ppt1-audio ppt2-audio ppt3-audio |
Assignment 2 Supplement 2 |
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Lecture 5, June 2 | |||
Lecture 6, June 9
[Swapped with lecture 7!] |
ppt1-audio | Assignment 3 Supplement 3 |
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Lecture 7, June 16 | |||
Lecture 8, June 23 | Assignment 4 | ||
Lecture 9, June 30 | |||
Lecture 10, July 7 | Assignment 5 | ||
Lecture 11, July 14 |