Bioinformatics 3

Wednesday, April 26th, 2:00 pm – 5:00 pm, E2 1, room 007

Familiarity with contents of Bioinformatik I and II. The students will have to complete programming assignments with Python. This course can be taken as part of the Master program Bioinformatics.

The course will cover methodological aspects of integrated biology and systems biology:

• protein-protein interaction networks (mathematical graphs, Bayesian networks)
• analysis of protein complexes (density fitting, Fourier transformation)
• transcriptional regulatory networks (Boolean networks) including epigenetic processes and micro RNAs
• dynamic simulation of cellular processes (differential equation solvers, stochastic simulations)
• metabolic networks (linear algebra)

Students need to pass the written final exam that will be scheduled near the end of the winter semester or the re-exam that will be scheduled at the beginning of the following summer semester.

At least half of the points of the assignments. Solutions have to be returned at the beginning of the following Friday`s lecture. In addition each student has to solve one of these problems on the blackboard.

V. Helms, Principles of Computational Cell Biology, Wiley (2008)

9 (4 V + 2 Ü)

This course is taught in English language.