Bioinformatics 3


Monday, 2:15 pm – 4:00 pm and Friday, 1:15 pm – 3:00 pm, building E2 1, room 007


Monday, 12 pm – 2 pm, E2 1, room 007


Friday, March 3rd, 10:00 am – 1:00 pm, building E2 1, room 007


Wednesday, April 26th, 2:00 pm – 5:00 pm, E2 1, room 007


Familiarity with contents of Bioinformatik I and II. The students will have to complete programming assignments with Python. This course can be taken as part of the Master program Bioinformatics.


The course will cover methodological aspects of integrated biology and systems biology:

  • protein-protein interaction networks (mathematical graphs, Bayesian networks)
  • analysis of protein complexes (density fitting, Fourier transformation)
  • transcriptional regulatory networks (Boolean networks) including epigenetic processes and micro RNAs
  • dynamic simulation of cellular processes (differential equation solvers, stochastic simulations)
  • metabolic networks (linear algebra)


Students need to pass the written final exam that will be scheduled near the end of the winter semester or the re-exam that will be scheduled at the beginning of the following summer semester.

Condition for participation in the final exam:

At least half of the points of the assignments. Solutions have to be returned at the beginning of the following Friday`s lecture. In addition each student has to solve one of these problems on the blackboard.


V. Helms, Principles of Computational Cell Biology, Wiley (2008)


9 (4 V + 2 Ü)


This course is taught in English language.


Lecture Slides (pdf) Slides (ppt) Assignments Supplements
Lecture 1, October 28  pdf  ppt  pdf  zip
Lecture 2, October 31  pdf  ppt
Lecture 3, November 4  pdf ppt  pdf  zip
Lecture 4, November 7  pdf ppt
Lecture 5, November 11  pdf  ppt   pdf  zip
Lecture 6, November 14  pdf  ppt
Lecture 7, November 18  pdf  ppt  pdf
Lecture 8, November 21  pdf ppt
Lecture 9, November 25  pdf  ppt  pdf  zip
Lecture 10, November 28  pdf  ppt
Lecture 11, December 2  pdf  ppt  pdf
Lecture 12, December 5  pdf  ppt
Lecture 13, December 9 pdf  ppt  pdf  zip
Lecture 14, December 12  pdf  ppt
Lecture 15, December 16  pdf  ppt
Lecture 16, January 2  pdf  ppt
Lecture 17, January 6  pdf  ppt  pdf  bonus
Lecture 18, January 9  pdf  ppt
Lecture 19, January 13  pdf  ppt  pdf
Lecture 20, January 16  pdf ppt
Lecture 21, January 20  pdf  ppt
Lecture 22, January 23  pdf  ppt  pdf  zip
Lecture 23, January 27  pdf  ppt
Lecture 24, January 30  pdf  ppt
Lecture 25, February 3  pdf  ppt